Bupivacaine Hydrochloride, Epinephrine Bitartrate Injection shortage
Current 20 presentations · 2 manufacturers · first FDA posting 2018-02-20 · last update 2026-10-15
Manufacturers: Fresenius Kabi USA, LLC, Hospira, Inc., a Pfizer Company
Stated reasons (per FDA): Delay in shipping of the drug; Demand increase for the drug; Other
Presentations
| Presentation | Manufacturer | Status | Reason | Notes (FDA) | Dates |
|---|---|---|---|---|---|
| Sensorcaine, Injection, 7.5 mg/1 mL; .005 mg/1 mL (NDC 63323-460-37) | Fresenius Kabi USA, LLC | Current Available |
— | Check wholesaler for inventory | Posted 02/20/2018 Updated 10/15/2026 |
| Sensorcaine, Injection, 2.5 mg/1 mL; .005 mg/1 mL (NDC 63323-461-57) | Fresenius Kabi USA, LLC | Current Unavailable |
Demand increase for the drug | Next release November 2026. Check wholesalers for inventory. | Posted 02/20/2018 Updated 10/15/2026 |
| Sensorcaine, Injection, 5 mg/1 mL; .005 mg/1 mL (NDC 63323-462-17) | Fresenius Kabi USA, LLC | Current Available |
— | Check wholesalers for inventory | Posted 02/20/2018 Updated 10/15/2026 |
| Sensorcaine, Injection, 5 mg/1 mL; .005 mg/1 mL (NDC 63323-462-31) | Fresenius Kabi USA, LLC | Current Unavailable |
Delay in shipping of the drug | Estimated recovery: TBD | Posted 02/20/2018 Updated 10/15/2026 |
| Sensorcaine, Injection, 5 mg/1 mL; .005 mg/1 mL (NDC 63323-462-37) | Fresenius Kabi USA, LLC | Current Available |
— | Check wholesalers for inventory | Posted 02/20/2018 Updated 10/15/2026 |
| Sensorcaine, Injection, 5 mg/1 mL; .005 mg/1 mL (NDC 63323-463-57) | Fresenius Kabi USA, LLC | Current Unavailable |
Demand increase for the drug | Next release October 2026. Check wholesalers for inventory. | Posted 02/20/2018 Updated 10/15/2026 |
| Sensorcaine, Injection, 2.5 mg/1 mL; .005 mg/1 mL (NDC 63323-468-17) | Fresenius Kabi USA, LLC | Current Available |
— | Check wholesalers for inventory | Posted 02/20/2018 Updated 10/15/2026 |
| Sensorcaine, Injection, 2.5 mg/1 mL; .005 mg/1 mL (NDC 63323-468-37) | Fresenius Kabi USA, LLC | Current Available |
— | Check wholesaler for inventory | Posted 02/20/2018 Updated 10/15/2026 |
| Marcaine With Epinephrine, Injection, Marcaine with Epinephrine 1:200,000 as the bitartrate 25 mg/10 mL (2.5 mg/mL 1:200,000) (NDC 0409-1746-10) | Hospira, Inc., a Pfizer Company | Current Available |
— | Posted 02/20/2018 Updated 10/08/2026 | |
| Marcaine With Epinephrine, Injection, Marcaine with Epinephrine 1:200,000 as the bitartrate 75 mg/30 mL (2.5 mg/mL 1:200,000) (NDC 0409-1746-30) | Hospira, Inc., a Pfizer Company | Current Available |
— | Posted 02/20/2018 Updated 10/08/2026 | |
| Marcaine With Epinephrine, Injection, Marcaine with Epinephrine 1:200,000 as the bitartrate 50 mg/10 mL (5 mg/mL 1:200,000) (NDC 0409-1749-10) | Hospira, Inc., a Pfizer Company | Current Available |
— | Posted 02/20/2018 Updated 10/08/2026 | |
| Marcaine With Epinephrine, Injection, Marcaine with Epinephrine 1:200,000 as the bitartrate 150 mg/30 mL (5 mg/mL 1:200,000) (NDC 0409-1749-29) | Hospira, Inc., a Pfizer Company | Current Available |
— | Posted 02/20/2018 Updated 10/08/2026 | |
| Marcaine With Epinephrine, Injection, Marcaine with Epinephrine 1:200,000 as the bitartrate 125 mg/50 mL (2.5 mg/mL 1:200,000) (NDC 0409-1752-50) | Hospira, Inc., a Pfizer Company | Current Available |
— | Posted 02/20/2018 Updated 10/08/2026 | |
| Marcaine With Epinephrine, Injection, Marcaine with Epinephrine 1:200,000 as the bitartrate 250 mg/50 mL (5 mg/mL 1:200,000) (NDC 0409-1755-50) | Hospira, Inc., a Pfizer Company | Current Available |
— | Posted 02/20/2018 Updated 10/08/2026 | |
| Bupivacaine Hydrochloride And Epinephrine, Injection, 25 mg/10 mL (2.5 mg/mL) (NDC 0409-9042-01) | Hospira, Inc., a Pfizer Company | Current Unavailable |
Other | Next Delivery and Estimated Recovery: December 2028; Shortage per Manufacturer: Manufacturing Delay | Posted 02/20/2018 Updated 10/08/2026 |
| Bupivacaine Hydrochloride And Epinephrine, Injection, 75 mg/30 mL (2.5 mg/mL) (NDC 0409-9042-17) | Hospira, Inc., a Pfizer Company | Current Unavailable |
Other | Next Delivery and Estimated Recovery: December 2028; Shortage per Manufacturer: Manufacturing Delay | Posted 02/20/2018 Updated 10/08/2026 |
| Bupivacaine Hydrochloride and Epinephrine, Injection, 125 mg/50 mL (2.5 mg/mL) (NDC 0409-9043-01) | Hospira, Inc., a Pfizer Company | Current Unavailable |
Other | Next Delivery and Estimated Recovery: December 2028; Shortage per Manufacturer: Manufacturing Delay | Posted 02/20/2018 Updated 10/08/2026 |
| Bupivacaine Hydrochloride And Epinephrine, Injection, 50 mg/10 mL (5 mg/mL) (NDC 0409-9045-01) | Hospira, Inc., a Pfizer Company | Current Unavailable |
Other | Next Delivery and Estimated Recovery: December 2028; Shortage per Manufacturer: Manufacturing Delay | Posted 02/20/2018 Updated 10/08/2026 |
| Bupivacaine Hydrochloride and Epinephrine, Injection, 150 mg/30 mL (5 mg/mL) (NDC 0409-9045-17) | Hospira, Inc., a Pfizer Company | Current Unavailable |
Other | Next Delivery and Estimated Recovery: December 2028; Shortage per Manufacturer: Manufacturing Delay | Posted 02/20/2018 Updated 10/08/2026 |
| Bupivacaine Hydrochloride And Epinephrine, Injection, 250 mg/50 mL (5 mg/mL) (NDC 0409-9046-01) | Hospira, Inc., a Pfizer Company | Current Unavailable |
Other | Next Delivery and Estimated Recovery: December 2028; Shortage per Manufacturer: Manufacturing Delay | Posted 02/20/2018 Updated 10/08/2026 |
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