Promethazine Hydrochloride Injection shortage
Current 10 presentations · 2 manufacturers · first FDA posting 2023-11-21 · last update 2026-10-14
Manufacturers: Hikma Pharmaceuticals USA, Inc., XGen Pharmaceuticals DJB, Inc.
Stated reasons (per FDA): Demand increase for the drug; Other
Presentations
| Presentation | Manufacturer | Status | Reason | Notes (FDA) | Dates |
|---|---|---|---|---|---|
| Promethazine Hydrochloride, Injection, 25 mg/1 mL (NDC 0641-0928-25) | Hikma Pharmaceuticals USA, Inc. | Current Unavailable |
Demand increase for the drug | Additional lots will be available in the October 2026 timeframe. Product will be made available as it is released. | Posted 11/21/2023 Updated 09/18/2026 |
| Promethazine Hydrochloride, Injection, 50 mg/1 mL (NDC 0641-0929-25) | Hikma Pharmaceuticals USA, Inc. | Current Limited Availability |
Demand increase for the drug | Estimated recovery: TBD | Posted 11/21/2023 Updated 09/18/2026 |
| Promethazine Hydrochloride, Injection, 25 mg/1 mL (NDC 0641-1495-35) | Hikma Pharmaceuticals USA, Inc. | Current Available |
Demand increase for the drug | Limited availability | Posted 11/21/2023 Updated 09/18/2026 |
| Promethazine Hydrochloride, Injection, 50 mg/1 mL (NDC 0641-1496-35) | Hikma Pharmaceuticals USA, Inc. | Current Available |
— | Additional lots are scheduled to be manufactured. Product will be made available as it is released. | Posted 11/21/2023 Updated 10/14/2026 |
| Phenergan, Injection, 25 mg/1 mL (NDC 0641-6082-25) | Hikma Pharmaceuticals USA, Inc. | Current Unavailable |
Other | Additional lots are scheduled to be manufactured. Product will be made available as it is released. | Posted 11/21/2023 Updated 09/18/2026 |
| Phenergan, Injection, 50 mg/1 mL (NDC 0641-6083-25) | Hikma Pharmaceuticals USA, Inc. | Current Unavailable |
— | Additional lots are scheduled to be manufactured. Product will be made available as it is released. | Posted 11/21/2023 Updated 09/18/2026 |
| Phenergan, Injection, 25 mg/1 mL (NDC 0641-6084-25) | Hikma Pharmaceuticals USA, Inc. | Current Unavailable |
Other | Estimated recovery: TBD | Posted 11/21/2023 Updated 10/14/2026 |
| Phenergan, Injection, 50 mg/1 mL (NDC 0641-6085-25) | Hikma Pharmaceuticals USA, Inc. | Current Unavailable |
Other | Estimated recovery: TBD | Posted 11/21/2023 Updated 10/14/2026 |
| Promethazine Hydrochloride, Injection, 25 mg/1 mL (NDC 39822-5525-3) | XGen Pharmaceuticals DJB, Inc. | Current Available |
— | Posted 11/21/2023 Updated 09/22/2026 | |
| Promethazine Hydrochloride, Injection, 50 mg/1 mL (NDC 39822-5550-6) | XGen Pharmaceuticals DJB, Inc. | Current Unvailable |
Demand increase for the drug | Estimated recovery: TBD | Posted 11/21/2023 Updated 09/22/2026 |
Get the weekly shortage roundup: a free email of FDA shortage changes (open form)