Sodium Bicarbonate Injection shortage
Current 15 presentations · 5 manufacturers · first FDA posting 2017-03-01 · last update 2026-10-15
Manufacturers: Amphastar Pharmaceuticals, Inc., Exela Pharma Sciences, LLC, Fresenius Kabi USA, LLC, Hospira, Inc., a Pfizer Company, Long Grove Pharmaceuticals LLC
Stated reasons (per FDA): Demand increase for the drug; Other
Presentations
| Presentation | Manufacturer | Status | Reason | Notes (FDA) | Dates |
|---|---|---|---|---|---|
| Sodium Bicarbonate, Injection, 84 mg/1 mL (NDC 76329-3352-1) | Amphastar Pharmaceuticals, Inc. | Current Limited Availability |
Demand increase for the drug | Available on allocation | Posted 03/01/2017 Updated 10/05/2026 |
| Sodium Bicarbonate, Injection, 84 mg/1 mL (NDC 51754-5001-5) | Exela Pharma Sciences, LLC | Current Available |
— | Posted 07/24/2017 Updated 10/15/2026 | |
| Sodium Bicarbonate, Injection, 84 mg/1 mL (NDC 51754-5011-4) | Exela Pharma Sciences, LLC | Current Available |
— | Posted 07/24/2017 Updated 10/15/2026 | |
| Sodium Bicarbonate, Injection, 42 mg/1 mL (NDC 51754-5012-4) | Exela Pharma Sciences, LLC | Current Available |
— | Posted 07/24/2017 Updated 10/15/2026 | |
| Sodium Bicarbonate, Injection, 42 mg/1 mL (NDC 63323-083-05) | Fresenius Kabi USA, LLC | Current Available |
— | Check wholesalers for inventory. | Posted 07/24/2017 Updated 10/15/2026 |
| Sodium Bicarbonate, Injection, 84 mg/1 mL (NDC 63323-089-50) | Fresenius Kabi USA, LLC | Current Available |
— | Check wholesalers for inventory | Posted 07/24/2017 Updated 10/15/2026 |
| Sodium Bicarbonate, Injection, 2.5 mEq/5 mL (4.2%, 0.5 mEq/mL) (NDC 0409-5555-01) | Hospira, Inc., a Pfizer Company | Current Limited Availability |
Other | Limited Supply Available. Next Delivery: May 2027; Estimated Recovery: June 2027; Shortage per Manufacturer: Manufacturing Delay | Posted 03/01/2017 Updated 10/08/2026 |
| Sodium Bicarbonate, Injection, 2.5 mEq/5 mL (4.2%, 0.5 mEq/mL) (NDC 0409-5555-02) | Hospira, Inc., a Pfizer Company | Current Available |
— | Posted 03/01/2017 Updated 10/08/2026 | |
| Sodium Bicarbonate, Injection, 50 mEq/50 mL (8.4%, 1 mEq/mL) (NDC 0409-6625-14) | Hospira, Inc., a Pfizer Company | Current Limited Availability |
Other | Limited Supply Available. Next Delivery: October 2026; Estimated Recovery: December 2026; Shortage per Manufacturer: Manufacturing Delay | Posted 03/01/2017 Updated 10/08/2026 |
| Sodium Bicarbonate, Injection, 50 mEq/50 mL (8.4%, 1 mEq/mL) (NDC 0409-6625-35) | Hospira, Inc., a Pfizer Company | Current Unavailable |
Other | Next Delivery: January 2027; Estimated Recovery: March 2027; Shortage per Manufacturer: Manufacturing Delay | Posted 03/01/2017 Updated 10/08/2026 |
| Sodium Bicarbonate, Injection, 84 mg/1 mL (NDC 81298-7620-3) | Long Grove Pharmaceuticals LLC | Current Available |
— | Posted 03/01/2017 Updated 10/01/2026 | |
| Sodium Bicarbonate, Injection, 84 mg/1 mL (NDC 0409-4900-14) | Hospira, Inc., a Pfizer Company | To Be Discontinued | — | Discontinuation of the manufacture of the drug | Posted 11/07/2025 Updated 11/07/2025 Discontinued 11/07/2025 |
| Sodium Bicarbonate, Injection, 75 mg/1 mL (NDC 0409-4916-14) | Hospira, Inc., a Pfizer Company | To Be Discontinued | — | Discontinuation of the manufacture of the drug | Posted 11/07/2025 Updated 11/07/2025 Discontinued 11/07/2025 |
| Sodium Bicarbonate, Injection, 42 mg/1 mL (NDC 0409-5534-14) | Hospira, Inc., a Pfizer Company | To Be Discontinued | — | Discontinuation of the manufacture of the drug | Posted 11/07/2025 Updated 11/07/2025 Discontinued 11/07/2025 |
| Sodium Bicarbonate, Injection, 84 mg/1 mL (NDC 0409-6637-14) | Hospira, Inc., a Pfizer Company | To Be Discontinued | — | Discontinuation of the manufacture of the drug | Posted 11/07/2025 Updated 11/07/2025 Discontinued 11/07/2025 |
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